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Show 4.16 7713 ‘Pdt/mlogie of the Spleen, 8m. Book I. Part I I I. qroweth more and more black and thick, and is at lafl concreted by Acid Particles into a hard fubi'tance, producing a Scirrhus. The fubjeét matter and the efficient caufe rendring the Spleen thculenr, and Scirrhous, dothonly differ in degrees, by reafon, I conceive, the Aéfive Principle that maketh the Blood grols and concreted, is Acidity, which is produced by Saline Particles brought to 3. Floor; which as it is more or lefs exalted, is the eflicieut of greater or lefs alterations in the Blood, ftagnatcd in the body of the Glands, appertaining to the Spleen ', whereupon it grow- eth fometimes more grofs, and other times more Coagulated, as it is acted with higher Saline Particles, brought to a greater Floor. 3321?; The material caufe (as Iapprehend ) produélive of greater or lefs Indu. :‘h‘eépdgrati- ration, and Coagulation of the Blood, may proceed from its more or leis Spletnim earthy Clamminefs, as ailociated with crude indigefled Chymc, not allimi. lated into Purple Li'iuor, whereby it lofeth its due Fermentation, and grow. eth grofs and difpirited, and apt to fiagnate in the Membranous Cells, and Glands of the Spleen 5 as being unable to be percolated through their fub- fiance, herein it being I'tagnated by reafon the Lympha being too thick, cannot be received into the Lymphatduéts, and the Blood being too Fazculent, cannot be admitted into the Minute Orifices of the Splenick Veins: Where- upon the extravafated Purple Juice, debafed with Saline Particles, put into a Fluor, by the lofs of its Motion, doth gain a greater Acidity, as it is more 7710 ‘Patbo/ogic of the Spleen, &c. thicker, and altogether Grumous, wholly Coagulate'd without any ferous parts fwimming upon the top of the Red CraiIament. And that a more clear- account may be given, of the various incrafIating vertues of divers kinds of Acid Liquors, the Axillary Arteries of both Trunks may be opened in a Sheep, and the hafty fireams of Blood may be received into divers Velfcls, bedewed with different Acids, giving variety of Coagulations to the Blood, which treat our Eyes with pleafurc and delight ; whereupon we may be induced to believe upon good grounds,that the Blood impelled by the Splenick Arteriesjnto the Membranous Cells and Glands of the Spleen, may receive greater and greater Blacknefs and Coagulation, as confederated with divers kinds of Acids, which fometimes lncraIIate, and render the Blood black and grumous,like melted Pitch,and Lees of Red Wine, and Other times wholly Concrete it, without any feparation of the Serous from the Purple Liquor; whence proceed great indurations of the Spleen and Seirrhous Tumours, produced by divers forts of Acid Recrements, endued. with higher and higher Incraflating, and Coagulating qualities. So that we may make this Inference, That Indurations, and Scirrhous Tumours of the Spleen, take their rife from grofs Blood, aflociated with Acid Recrements, and Itagnated in the Membranous Cells and Glands, whereby the Extravafated Blood by its longer and longer Pray, receiveth higher de~ when they are long acted with this difaflbfied Blood, a Fever arifeth7 and grees of Acidity, inducing greater Induration, and Scirrhous Tumours, which are often accompanied with an Atrophy, and Aftitir, proceeding from a vitiated gtofs Mafs of Blood, whofe warty Particles are not feparated in the maketh a great Ebullition, whence its more moifl: Particles are confumed, and the Spleen becometh Indurated and Scirrhous, proceeding chiefly from nary Duels, and Papillary Caruncles, into the (Pele/it. and more ftagnant in the Pareuchyma of the Glands. . $32312; Book I. Part I II, 2:23:31" Blood concreted by its Acid Recrements. So that fometimes, Glands of the Kidneys, and thence conveyed through the Roots of the Uri- This Hypothefis hath been made A Noble Perfon being very much Emaciated, and having a dark yellowifh good by the injeéiion of Acid Liquors, into the Blood Veflels of Animals, Countenance, was aflliéted with a great Swelling in his Left Hypocondre, which are killed fooner or later, as the injeéled Liquors participate of greater or lefs Acidity: And the bodies of Bruits being opened, prefently after they were killed, to fee the caufe of their Death, the Blood was found concre- and his lean Thighs and Legs, did fwell a little before his Death; and the ted in the Afcendcnt and Defcendent Trunk of the C4714, and right Ventricle of the Heart. grgnfx‘pfgl-mg The truth of this AiIertion, may be farther evinced by this experiment of Colicrciion putting Ver}uice, the Juice of unripe Grapes, Juice of Linions, deflilled QUEST??? Vinegar, Spirit of Vitriol, Spirit of Sulphur, Spirit of Salt, Spirit of Nitrc, 9""‘5* into a Porringer, and then let the Blood fireain out of a healthy Mans Arm, or any other part into it, and the Blood becometh black, and of a greater Confifience, by reafon its fluid parts are prefently incraflated, fomewhat refembling melted Pitch, or the Lees of deep Red Wine 3 and as Blood is let out upon more mild or firong Acid Liquors, in greater or lcfs proportion, you may obferve various degrees of Blacknefs, and Confidence; In {trong Acid Spirits of Vitriol, and Nitre, the Blood is wholly Coagulated, both in its Purple and Serous parts. Acids work the fame effect in Arterious Blood, which is let out of the Temporal Artery, (a branch of the External Carotides) upon Inflammations of the Eyes, and great pains in the Head, (9'6, which I have often ordered with good Succefs. Afigridiiiioii. A farther Experiment may be offered, in befptinkling one Porringcr with scis'rorréor drops of Juice, fqueefed out of unripe Grapes, and another with Vinegar, into $123332} which Blood being immittecl'out of afound young Man, by opening aVeini in the firft Porrin‘ger, the Blood was clothed Wilh' black, and full of drag: like Lees of Wine 5 in the fecend, the Blood was found much blacker End - ., _ thit‘ 'er. fore parts of his Legs were vexed with angry Blifi'ered Tumours, the attendants of an Eryfipclnr, and fore-runners of his Departure. Afterward his Belly being opened, (firearms of clear Water guihed out ) in which no Omentum was found, which is commonly putrid in Dropfies; and then the Mufcles of the Abdomen being cut in manner of a Crofs, an indurated Scirrhous Spleen appeared, tied to the Left Hypoconder by great variety of Fibres, and its fubi'tance Within was Black and Putrid, and the Spleen refembled a Turbat in Figure, as being fomewhat Quadrangular, and equal in length and breadth. 4.27 |
