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Show PartsofAnimalsmixed= Le, IL ter. Medicines in the world, than fome certain Preparations of Nitre duly adminiftred. Whoeverfhall think that any kind ofacid, as Oy! of Sulphur, Oyl of Vitriol, Spirit of Salt, or the like, will have the fame effects, will find themfelves much deceived in their praétice, 5. Iconclude with Stones.’ And firft, Spirit of Nitre droped upe of the Kidneys or Bladder, produceth the very fame effet, as velin Urine. That is to fay, it makes it boil and huff’ up. until at leneth it is perfedly diffolued into a oft Pulp; which neither Oy! ofSulphur, sor Oyl of Vitriol, nor Spirit ofSalt will dos nor give the leaft touch towards its diffolution. This confirms what I faid before of the ufe of Nitre and Nitrous Spirits, if duly prepared and adminiftred, a- bove anyother Acids, again{t the breeding of the Stone. 43. §. fler-fhells. Pearls, with any Acid, make the like Effervefcence, as do OyBut Magistery of Pearls, as ufually prepared, ftirs not at all, ‘with any Alkaly or Acid, So that as to the effe& frequently intended by it, it is very infignificant ; as of that of Cors/s hath beenfaid, 44. §. Crabs Eyes, with any Acid, make an Effervefcence, alo, quick as that of Oyfter-fhells. “ ae ae 45. Crabs Eyes likewife calcined, make a ftronger Efferve(nence, than when uncalcined. So that thefe, as well as Shells, contain a fixed Alkaly, 46. §. The Stones in Whitings heads make a ftrong Effervefce: like that ofOyfter-fhells. : ae ee 47. §. Stone of humane Gall, Stirs not with Oyl ofVitriol. But with Spirit of Nitre maketh a little bullition juft upon mixing, andafter a confiderable time, alittle froth. Much lefs than what was obferved before of the Gall it felf. So thatit feemeth to be generated of the Gall coagulated by fome Acid, which hath already refrailed the Alkaly wherewith the Gall abounds. This confirms the ufe ofthofe Medicines in the anndies, or anyother bordering Diféafé, which deftroys thofe Acidities by which the Gall is curdled or coagulated, and fo rendred more difficulty feparable into the Guts. 48. §. Since the firft publifhing of thefe Obfervations, Mr. Wiliiane Matthews an Apothecary in Ledbury, fent me part, as I take it; ofa Stomach-ftone, as big as a Wallnut ofthe largeft Size, voided by a woman about 82 years of age, fometime after an Avtumu Fever. It confifteth of the fame Strie, as the Bezoar Stone; and maketh fome Bulfi- tion with Spirit of Nitre. 49. §. Bezoar, neither the Weitern nor the Eaftern, doth ftir at all with Oyl ofVitriol, 50. §. Western Bexoar, with Spirit ofNitre, makes avery little thin froth, andthat's alls and that it doth very flowly. But Oriental Bexoar, with Spirit of Nitre; after fome time, maketh a very great Effervefcence, froth, elevation, noife, andfteams (asifyou poured Oylof Vitriol upon Salt of Tartar ) till it be wholly diffolved by the affufed Spirit, andturned inte almoft a blood-red. Hence it may feem tobe no mean Remedy again{t fuch fretting and venenate acids, as oftentimes in Fevers, and other DiJftempers, lye about the stomach, and are thence frequently tranflated to the Heart, Brain, Nerves, and other parts. The difference likewifé betwixt the Wefterz and the Eaftern Bezoar, is fo great, that in any cafe of danger, and where the Bezoar is relyed upon, it is an Oe able LedIL with feveral Menstruums. able fault, forthe Apothecary, or any Perfox, to fubjtitute the one for theother: unlefs he will take tev times as much, or tex times as little of the one, as he would havedone ofthe other : if that will ferve turn 5i. §. The Stones already mentioned, (except the great Stozachftone are ordinarily generated in the bodies of Avimals. Ihave one Inftance more of fome other Stoves which are extraordinary. In the City of Hereford lives a Maid, whooften voids thefe Stoves, and in the {pace of fome years laft paft, hath voided fevetal pounds, of feveral Colours and Sizes, not only per vias urixarias, but alfo by vomit, and byftool, The firft mention made to me of them, was by Mr. Diggs,a worthy Gentleman ofthat City, as.a thing that was there much wondred at. And fome of them, upon my defire, were fent me by Mr. Wellington, an Apothecary inthe fame place. I have tryed what feveral acid Menftrunms will work upon them; and find, That with Oyl of Vitriol, and efpeially with Spirit of Nitre the great ones make a very quick and confpicuous Effervefcence. But the fmall ones, neither the white, nor the grey, make any Bullition inthe leaft: for in truth, they areno otherbutlittle Pebbles and Grit-ftoxes, 52. §. This being confiderd, and the various colours and mixture of any oneof the great Stoves, being well obferved ; it feemeth plain, Thatalthough fhe be fomewhat old (above thirty years ) yet mayfhe have akind of paraniz, or difeafed Appetite to Stones, Bones, Woodafhes, Tobacco-Pipes, Chalk, and fuch like things; which fometimes {wallowing in little vps, fometimes grofly, or finely ground betwixt her teeth; they are in her Stomach and Bowels, more or fewer of them, cemented together, either with a pituitous, bilious, or fome other more or lefS glutinows fubftance. And that by virtue alfo of the faid Cement, or anyofthe faid, or other like alkalizate Bodies, the greater Stones, which confift ofthofe partly, do make an Effervefcence with acid Limors. Thus far of Inftances upon the parts of Avimals, 1 {hall clofe with fomeCorollaries deduced from the whole. 53. §. And firft, fince we find, that amongftall the Mex/tuums we have made ufé of, Spirit of Nitre, or any very Nitrous Spirit, is the molt wziverfal diffolver of all kinds of Avimal Bodies; the beft diffolver of many others both Vegetable and Mineral, and the only diffolver of fome: Hence it is probable, That the great flomachick Menftruum, which either diffolves, or opens almoft all Bodies which come into the Stomach, is a kind of Nitrous Spirit. 54. §. Again, Spirit of Nitre being a fubalkaline Acid, and working more evidently upon Avimal bodies, than other fimpler Acids do, which yet are as ffromg; It hence follows, That moft of the Sa/ts of Animals are Jubacid Alkalies. Howfar this conclufion may further in- ftru& us, I fhall have occafion to fhewin another Difcour{é. 55. §. Laftly, there being fo many, fay twenty or thirty degrees, from the foweft to the moft vehement, in the Bullition of mixed Bodies 5 itfeemeth, That Fermentation it felf, as to the formal notion ofit, is nothing |