| OCR Text |
Show 28 Figure 2.3. Eticlopride pretreatment attenuates OAT complex formation (panel 8), the decreases in eH]DA uptake (panel C), and the OAT monomer loss following METH treatment (panel D). Rats received four injections of METH (7.5 mg/kg/injection; s.c.; 2-h intervals) or saline vehicle (1 ml/kg/injection; s.c.; 2-h intervals) and were sacrificed 24 h later. were Thirty min prior to each injection, rats pretreated with eticlopride (ETIC; 0.5 mg/kg/injection; i.p.) or saline vehicle (1 ml/kg/injection; i.p.). Panel A presents a representative blot of saline/saline (lane 1), saline/METH- (lane 2), ETIC/saline- (lane 3), and ETIC/METH- (lane 4) treated samples. blot. Molecular weight (kDa) is shown adjacent to a representative Columns represent the means and vertical lines 1 SEM determinations in 17 -23 rats. *Values different from saline-treated controls different from saline/METH-treated group (p s 0.05). (p s 0.05); tvalues |
