Methamphetamine-induced dopamine transporter complex formation and neurotoxicity

Methamphetamine (METH) is a highly addictive psychostimulant. METH use and abuse is a growing concern within the United States and throughout the world. In addition, repeated high-dose administrations of METH have been shown to cause persistent striatal dopaminergic deficits in humans, nonhuman primates, and rodents.