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Show Titles and Abstracts 145 Studies on Antibiotic Production by a Member of the Phycomycetes Don C. Wood, D. A. Anderson and T. L. Martin Brigham Young University A mold belonging to the Phycomycetes and tentatively iden tified as Rhizopus nigricans has been found to produce consider able quantities of an antibiotic substance when grown on the fol lowing media: 2 % corn .steep liquor pl us 2 % lactose; 3 % sugar beet molasses with 3 % stryptone and 2 % lactose; 3 % asparagus with 2 % lactose, and 1 % peptone. Several other media butt juice also showed antibiotic production. penicillin producing strain of Penicillium notatum when grown on the same media gave yields of penicillin similar in amount and inhibiting power to the antibiotic produced by Peni Rhizopus. When compared with the penicillin produced by Known cillium notatum, the antibiotic was found to be similar in many showed the same anti respects. Against seven different bacteria it biotic effect as penicillin. The solubility in several organic sol vents and in water was identical with that of commercial penicil lin. It showed the same response to heating as that of the peni cillin in the Penicillium notatum cultures. When treated with Clarase lot Schenley penicillinase and the penicillinase found in the antibiotic disappeared. Inactivation of the 1351, property by penicillinase is considered a reliable qualitative for penicillin. antibiotic test anti On the basis of these results it was concluded that the of biotic found is apparently a type of penicillin. This may be reviewed reveals no report far thus literature the since significance of a penicillin producing strain of Rhtzopus niqticans. The Influence of Azotobacter and Other Bacteria Proliferation of Mold Mycelia on Franklin H. Allen, D. A. Anderson and T. L. Martin Brigham Young University The present knowledge of antibiosis suggests the possibility soil molds may be inhibited or stimulated by the that metabolites of other micro-organisms. In line with this assump certain bacteria on tion, a study was made of the influence of of some common molds. The procedure consisted of the common growth |
