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Title Mystery of DNA replication, The
Subject DNA--Synthesis
Description The 43rd Annual Frederick William Reynolds Lecture.
Creator Lark, Karl G.
Publisher University of Utah Press
Date 1980-03-05
Date Digital 2008-05-29
Type Text
Format application/pdf
Digitization Specifications Original scanned on Epson Expression 10000XL flatbed scanner and saved as 400 ppi uncompressed tiff. Display images generated in PhotoshopCS and uploaded into CONTENTdm Aquisition Station.
Resource Identifier,83
Source QP624 .L37
Language eng
Relation Digital reproduction of "The Mystery of DNA replication," J. Willard Marriott Library Special Collections
Rights Digital Image Copyright University of Utah
Metadata Cataloger Seungkeol Choe; Ken Rockwell
ARK ark:/87278/s65q4t2n
Setname uu_fwrl
Date Created 2008-07-29
Date Modified 2008-08-04
ID 319398
Reference URL

Page Metadata

Title Page2
Description 2 KARL G. LARK The Early Days December 18, 1951, was a busy but pleasant day in an otherwise harrassed period of my life. At noon I was married at City Hall and that afternoon I attended a lecture by Max Delbriick at Columbia University. Max Delbriick was the founder of the phage group and had originated a course in bacteriophage (or phage) which was taught each summer by my major professor, Mark Adams. Bacteriophages were viruses which attacked bacteria and were composed of only nucleic acids and proteins. The course had attracted physicists, geneticists, microbiologists, and biochemists (like Adams himself, who was a physical biochemist). All believed that these viruses were simple enough to allow scientists to resolve the problems of heredity and biological organization. Because they came from so many different scientific disciplines, they viewed and discussed these problems collectively with a broad perspective seldom encountered in biology. I had met both my wife and Max Delbriick at Cold Spring Harbor a year and a half earlier, just before I entered graduate school at N.Y.U. Now I was in the process of taking my doctoral preliminary exams; I had completed my writtens but was looking forward with trepidation to the oral exam scheduled for January. For the exams I had studied the latest information that a student in the phage group was expected to know: that enzymes were the machines that directed the activities of a cell, that they were proteins, and that each protein was a string of amino acids folded into a unique configuration which could be destroyed by heating. I even knew that the structure of proteins and other large regular molecules might be understood using x-ray diffraction because Ast-bury had given a lecture in New York describing the use of x-ray diffraction to study the structure of hair. I knew also that the heredity of a cell was contained in genes which were strung together like beads on a string. At this time, it was still not known whether protein or nucleic acid was the genetic material. Students at N.Y.U. were familiar with the data in favor of DNA because our department head, Colin
Format application/pdf
Identifier 008-RNLT-LarKK_Page2.jpg
Source Original Manuscript: The mystery of DNA replication by Karl G. Lark.
Setname uu_fwrl
Date Created 2008-07-29
Date Modified 2008-07-29
ID 319363
Reference URL