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Show 142 Alden Smith school of medicine and health sciences Colorectal cancer is the second leading cause of cancer death in the United States, but is one of the most preventable cancers with early detection yielding a 92% 5-year survival rate. Those with an immediate family member diagnosed with colorectal cancer have at least a 2-to 3-fold increased risk for develop-ing colorectal cancer compared to the general population, however adherence to regular colonoscopy screening among these families is significantly below recommended levels. The purpose of the multi-site Family Colorectal Cancer Awareness and Risk Education (FCARE) randomized trial is to test the efficacy of telephone-based individualized cancer risk assessment as an alternative to in-person risk counseling services in promoting appropriate cancer screening. Members of families at a higher risk for colorectal cancer who enroll in the study initially complete a baseline questionnaire that elicits sociodemographic and clinical information as well as knowledge, attitudes and beliefs about colorectal cancer. Next, they are randomly assigned to receive either the minimal intervention consisting of a mailed educational brochure about colorectal cancer and screening or a more intensive intervention. This includes the same educational brochure along with a personalized telephone-based genomic cancer risk assessment and behavior change counseling with a cancer risk specialist followed by mailed personalized print materials. The TELECARE session counselor educates participants about their individual cancer risk considering their family history, assesses their concerns about colorectal cancer and encourages screening through colonos-copy using motivational interviewing techniques. All participants complete follow-up questionnaires 1, 9 and 15 months after the intervention or until a colonoscopy is reported. This trial will determine whether remote personalized cancer risk communication is more effective in promoting colonoscopy than targeted intervention (a mailed educational brochure). It is also expected to demonstrate a higher quality of informed decision-making among those receiving the TELECARE reflected in improved knowledge and colorectal cancer belief levels, more accurate risk perceptions, and lower psychological distress and decision conflict. Our study also compares recruitment levels and protocols from participating cancer registries, which illustrates specific factors determining recruitment success. These results may impact the design and implementation of future studies using cancer registries for case recruitment. IMPACT OF REMOTE FAMILIAL COLORECTAL CANCER RISK ASSESSMENT AND COUNSELING ON SCREENING BEHAVIOR Alden Smith (Anita Kinney) Department of Internal Medicine University of Utah UNDERGRADUATE RESEARCH ABSTRACTS Anita Kinney |
