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Title Chemical keys to an understanding of life processes
Subject Biochemistry ; Nucleic acids; Proteins
Description Twenty Second Annual Frederick William Reynolds Lecture.
Creator Smith, Emil L., 1911-
Publisher Extension Division, University of Utah
Date 1958-01-13
Date Digital 2008-05-29
Type Text
Format image/jpeg
Digitization Specifications Original scanned on Epson Expression 10000XL flatbed scanner and saved as 400 ppi uncompressed tiff. Display images generated in PhotoshopCS and uploaded into CONTENTdm Aquisition Station.
Resource Identifier,564
Source LD5526.U8 n.s. v.49 no.11
Language eng
Relation Digital reproduction of "Chemical keys to an understanding of life processes," J. Willard Marriott Library Special Collections
Rights Digital Image Copyright University of Utah
Metadata Cataloger Seungkeol Choe; Ken Rockwell
ARK ark:/87278/s6c8277g
Setname uu_fwrl
Date Created 2008-07-29
Date Modified 2008-07-31
ID 319868
Reference URL

Page Metadata

Title Page16
Description 16 TWENTY-SECOND ANNUAL REYNOLDS LECTURE enzymic structure and function. We need not be concerned with the entire protein structure but only with the active portion of the molecule. Secondly, the results show what has been suspected for some time, that proteins contain an active site, namely a specific region of the molecule which contains the specificity information and the catalytic ability. Many different approaches and many different methods are being employed at present in our attempts to understand the functional ability of enzyme molecules. All of the currently available tools of the chemist and physicist are being brought to bear on this problem. For with an understanding of enzyme structure and function we feel that we shall be close to an understanding of one of the major aspects of life itself. VI The miracle of the living cell is the coordinated metabolic activity by which the cell maintains itself, grows and divides giving rise to an identical pair of daughter cells. This is a miracle of the biosynthesis of protein. Growth in essence means the formation of new protein molecules possessing the same structure and catalytic activity as the sister molecules. How are these complex protein molecules synthesized in such a way that the exact specificity and arrangement of the amino acids is always reproduced ? And what happens if it isn't so reproduced ? To attempt to answer these questions we must turn to what Genetics has taught us. The study of the mode of inheritance of biological properties constitutes the science of Genetics. Much is already known concerning the nature of inheritance. It is known that most genetic factors or genes are carried in the nucleus of the cell and that certain bodies called chromosomes contain the genes. Inasmuch as the metabolic machinery of the cell consists of complex chemical compounds called proteins, the units of inheritance must determine the biochemical synthesis of protein. Thus, the units of inheritance themselves must be chemical compounds. It should be apparent that only molecules as large as the proteins and as specific in their structure can be visualized as in some way determining protein or enzyme synthesis. Chromosomes consist mainly of proteins combined with distinctive high molecular weight compounds called nucleic acids; these are quite different from proteins in chemical structure. Nucleic acids
Format image/jpeg
Identifier 021-RNLT-SmithE_Page16.jpg
Source Original Manuscript: Chemical keys to an understanding of life processes by Emil L. Smith.
Setname uu_fwrl
Date Created 2008-07-29
Date Modified 2008-07-29
ID 319857
Reference URL