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Show THE UNIVERSITY OF UTAH HEALTH SCIENCES LEAP PROGRAM DISCOVERING THE MOST EFFECTIVE PROCESS MEASURING DIRECT BONE CONTACT Felix I. Vivanco, (Sujee Jeyapalina, Roy D. Bloebaum) Department of Orthopedics University of Utah To access compatibility of a n e w material and design parameters of an orthopaedic implant, appositional bone index (ABI) is often used to evaluate the degree of osseointegration during the translation research. For the quantification, the contact radiographs are used often to determine the percentage of direct bone contact with the implants, but this technique has its limitations. There are also several other techniques available for determining the ABI. They include: scanning electron microscopy (SEM), photomicrographs etc. The accuracy of each of these techniques has yet to be experimentally assessed. In order to determine the best technique for accurately acquiring ABI data, the current research has been undertaken. In this study, three different techniques were employed obtain ABI data to determine the accuracy each technique. Bone -implant interfaces of 33 sheep were randomly selected from a larger study, which consisted of 85 animals with different post-operative implantation times of 3, 6, 9, and 12 months. This is an on-going study, and currently, w e have only measured the ABI values from contact radiographs (n=???). Obtaining ABI data from SEM and light micrographs are ongoing. It is expected that data from the light microscopy will be the most accurate one, because it will accurate differentiate bone (red) from fibrous capsule (blue) at the interface, when Sanderson bone stainTM is to be used. Roy D. Bloebaum 175 |
