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Title Exploring human heredity
Subject Heredity, Human; Medical genetics; Adaptation (Biology)
Description Twentieth Annual Frederick William Reynolds Lecture.
Creator Stephens, Fayette Ellsworth, 1890-
Publisher Extension Division, University of Utah
Date 1956-01-16
Date Digital 2008-05-29
Type Text
Format image/jpeg
Digitization Specifications Original scanned on Epson Expression 10000XL flatbed scanner and saved as 400 ppi uncompressed tiff. Display images generated in PhotoshopCS and uploaded into CONTENTdm Aquisition Station.
Resource Identifier,362
Source LD5526 .U8 n.s. v.47 no.11
Language eng
Relation Digital reproduction of "Exploring human heredity" J. Willard Marriott Library Special Collections
Rights Digital Image Copyright University of Utah
Metadata Cataloger Seungkeol Choe; Ken Rockwell
ARK ark:/87278/s64q7rxv
Setname uu_fwrl
Date Created 2008-07-29
Date Modified 2008-07-31
ID 319670
Reference URL

Page Metadata

Title Page14
Description 14 TWENTIETH ANNUAL REYNOLDS LECTURE and found free of the disease. Their next question was, "Could he transmit the trait to his children?" When told that he had drawn the normal gene instead of the affected one and therefore was no more apt to transmit the defect than any other normal person, they said, "We must not let our daughter hear about this. She was engaged to this young man, and we broke up the match for fear that their children would have this hereditary disease." There is good indication that in many instances people fail to marry or, if they do marry, fail to have children for fear that some hereditary trait found in their family will be transmitted to their children, when actually there may be no chance at all of its happening. The pattern of inheritance of a given trait is determined in part by the location of its gene on the chromosome. In man both members of each pair of the twenty-four pairs of chromosomes are alike, with the exception of one pair, the sex chromosomes. In the male this pair is made up of an X and a small Y chromosome. In the female it is made up of two X chromosomes. Genes may be located on the X chromosome only, on the Y chromosome alone, or on both the X and the Y chromosomes. The manner in which they are located can be determined by the way in which the trait is transmitted. Approximately thirty human genes are known to be located on the X chromosome and not on the Y chromosome. This is probably only a part of those actually located there. These genes are known as sex-linked genes, and the traits they produce are called sex-linked traits. Most of these are recessive. Such traits as red and green color blindness and hemophilia are inherited in this manner. Two sex-linked traits which we have studied in our laboratory are Microphthalmia and Choroideremia. They are types of hereditary blindness. These traits are due to the action of two different genes, both located on the X chromosome. The gene for Microphthalmia produces a form of congenital blindness shown in Figure 3. The eye ball is small and so covered with abnormal tissue that the individual is completely blind from birth. Figure 4 shows a pedigree history of this family. Here the trait occurs only in males, but is transmitted by the females. These females are known as carriers because they carry the defective gene but do not show the trait. There is no known way of distinguishing them from their sisters who are not carriers except by their male offspring. When this study was first made, a sister of two blind brothers was told that she had an equal
Format image/jpeg
Identifier 014-RNLT-StephensF_Page14.jpg
Source Original Manuscript:Exploring human heredity by Fayette E. Stephens.
Setname uu_fwrl
Date Created 2008-07-29
Date Modified 2008-07-29
ID 319648
Reference URL