| Title | Journal of Neuro-Ophthalmology, March 2008, Volume 28, Issue 1 |
| Date | 2008-03 |
| Language | eng |
| Format | application/pdf |
| Type | Text |
| Publication Type | Journal Article |
| Collection | Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher | Lippincott, Williams & Wilkins |
| Holding Institution | Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management | © North American Neuro-Ophthalmology Society |
| ARK | ark:/87278/s6vt4z6b |
| Setname | ehsl_novel_jno |
| ID | 225680 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s6vt4z6b |
| Title | Isolated Lymphoma of the Anterior Visual Pathway Diagnosed by Optic Nerve Biopsy |
| Creator | Zelefsky, JR; Revercomb, CH; Lantos, G; Warren, FA |
| Affiliation | Department of Ophthalmology, New York University School of Medicine, New York, New York 10016, USA. jzelefsk@yahoo.com |
| Abstract | A 72-year-old previously healthy man developed rapidly progressive visual loss, and brain imaging showed features suggestive of a malignant glioma of the anterior visual pathway. Biopsy of one optic nerve yielded a diagnosis of lymphoma. There was no evidence of an extracranial non-Hodgkin lymphoma, so the conclusion was that this represented a primary central nervous system lymphoma (PCNSL). PCNSL isolated to the optic chiasm has been described only once in an immunocompetent patient. Our patient is unusual in that the lymphoma involved the optic nerve, chiasm, and tract in an immunocompetent patient. |
| Subject | Older people; Antigens, Neoplasm, analysis; Antigens, Neoplasm, immunology; Antimetabolites, Antineoplastic, therapeutic use; Antineoplastic Agents, Hormonal, therapeutic use; Biopsy; Diagnosis, Differential; Disease Progression; Fatal Outcome; Humans; Leucovorin, therapeutic use; Lymphoma, B-Cell, diagnosis; Lymphoma, B-Cell, physiopathology; Magnetic Resonance Imaging; Male; Methotrexate, therapeutic use; Neoplasm Invasiveness, pathology; Optic Chiasm, pathology; Optic Chiasm, physiopathology; Optic Nerve, pathology; Optic Nerve, physiopathology; Optic Nerve Neoplasms, diagnosis; Optic Nerve Neoplasms, physiopathology; Prednisone, therapeutic use; Treatment Failure; Tumor Markers, Biological, analysis; Tumor Markers, Biological, immunology; Vision, Low, etiology; Vision, Low, pathology; Vision, Low, physiopathology; Vitamin B Complex, therapeutic use |
| Format | application/pdf |
| Publication Type | Journal Article |
| Collection | Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher | Lippincott, Williams & Wilkins |
| Holding Institution | Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management | © North American Neuro-Ophthalmology Society |
| Setname | ehsl_novel_jno |
| ID | 225668 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s6vt4z6b/225668 |