| Title |
Bilateral Simultaneous Central Retinal Artery Occlusions in Wegener Granulomatosis |
| Creator |
Costello, F; Gilberg, S; Karsh, J; Burns, B; Leonard, B |
| Affiliation |
The Ottawa Hospital, Department of Ophthalmology, University of Ottawa, Ottawa, Ontario, Canada. fcostello@ottawahospital.on.ca |
| Abstract |
A 46-year old woman developed simultaneous central retinal artery occlusions (CRAOs) in Wegener granulomatosis (WG). She had presented six years earlier with xerostomia, skin rash, and arthralgias and received a diagnosis of Sjogren syndrome. Anti-neutrophilic cytoplasmic antibody (ANCA) was negative. Months prior to the CRAOs, she had developed hearing loss, proptosis, and scleritis that were not responsive to prednisone 50 mg/d. The CRAOs occurred while she was being treated at this dose level. ANCA was now positive. This is the 12th case of CRAO in WG and the 6th case of bilateral CRAOs reported in the English literature. It emphasizes that serious irreversible visual complications may occur even when the patient is being treated with substantial corticosteroid doses. |
| Subject |
Antibodies, Antineutrophil Cytoplasmic, blood; Dose-Response Relationship, Drug; Female; Glucocorticoids, administration & dosage; Glucocorticoids, therapeutic use; Humans; Middle Older people; Prednisone, administration & dosage; Prednisone, therapeutic use; Retinal Artery Occlusion, etiology; Retinal Artery Occlusion, pathology; Retinoscopy; Treatment Failure; Wegener Granulomatosis, complications; Wegener Granulomatosis, drug therapy; Wegener Granulomatosis, immunology |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225416 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6dr61jp/225416 |
