| Title |
Nonarteritic Ischemic Optic Neuropathy Developing Soon After Use of Sildenafil |
| Creator |
Pomeranz, HD; Bhavsar, AR |
| Affiliation |
Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, MN 55455, USA. pomer010@umn.edu |
| Abstract |
Seven patients, aged between 50 and 69 years, had typical features of nonarteritic anterior ischemic optic neuropathy (NAION) within 36 hours after ingestion of sildenafil citrate (Viagra) for erectile dysfunction. Six patients had vision loss within 24 hours after use of the agent. Final visual acuity in the affected eye ranged from 20/20 to light perception. Both eyes were affected in one individual. All affected individuals had pre-existing hypertension, diabetes, elevated cholesterol, or hyperlipidemia. Seven similar cases have been previously reported. Sildenafil may provoke NAION in individuals with an arteriosclerotic risk profile. |
| Subject |
Older people; Humans; Male; Middle Older people; Optic Neuropathy, Ischemic, chemically induced; Optic Neuropathy, Ischemic, physiopathology; Phosphodiesterase Inhibitors, adverse effects; Piperazines, adverse effects; Purines; Sulfones; Visual Acuity; Visual Fields |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225411 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6dr61jp/225411 |
