| OCR Text |
Show 175 percentage of tyrosyl, tryptophan and histidyl residue (all containing five of six member aromatic ring systems)o and CD of these protens with the ORD or CD of their apoprotein and amino acid residues may involved in the , 29 (1961)Jo the CP of CP and its binding of the Moreover there Fe(II), Ni(II) and Co(II), 1.lO-phenanthrolineo The Reaction of The residues of pH and spectro apoprotein have already suggsted copper [So are or numerous in the protein are Osaki, So BiochemQ compounds which such Tokyo, affect anions like as Cl-, N03-; polyacids like malic, fumaric and oxalic, metal ions Our importance Mercury(II) of and copper ion chelators like EDTA proposal would include inhibitors in solution with the 60 Comparison copper 0 activity, principally as inhibitors, SCN- and and specific residue to the histidyl, lysyl or the tyrosyl residues concerned with the like point binding of the photometric titrations that Comparison of the ORD. study of these Ceruloplasmino with Nucleosides of the understanding an a interaction of metal ions with nucleic acids becomes evident when it is realized that metals of various the structure 0 on under various conditions, can secondary and t,ertiary macromolecular structure, these structures, the kinds, or even Of fundamental bring about the importance to or decomposition such an stabilize labilize of the understanding primary is knowldge of whether the metal ions bind to the phosphate goups the polynucleotide chain, or whether they bind to electron donors |
