| OCR Text |
Show 89 .. . ....... o (,) (b) 6-substiuted purine a-substituted adenine o----------------------- )«, ('t) • -2 o r-f x -4 < -6 20 40 m m\';I.,.' The ampl,i,tuae of the B Cotton effect of Figure 'and' 8-substitu.fd adenine nucleosides 6-substitute,d, purines as a function of the spectroscopic moment (m) of the substituent" 5051'1 ' think of the two series 6- and crease 8-substituted as representing the substituent effects on purineo the rotation with Substituents in the 6-pesition in increasig magnitude of their spectroscopic moments while 8-substitution decreases the rotation with increasing magnitude of the spectroscopic momentsQ, A possible interpretation I is that in one case the polarization angl, is rotated clockwise and in the other anticlockwiseo an This interpretation extrapolation of the theory of Platt, has been observed that I' is supported by Moffitt and Petruskao It glyoxaline I,benziminazole II, and purine III |
