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Show LITERATURE ABSTRACTS 133 cluding meningitis with papilledema, optic neuritis, sixth nerve palsy, and neuroretinitis. These complications developed between 1 week and 8 months after onset of Lyme disease; thus the authors stress that it behooves the neuro- ophthalmologist to be alert to the possibility of this disease with these disorders. Lyn A. Sedwick, M. D. Hemifacial Spasm in Infancy. Flueler U, Taylor 0, Hing S, Kendall B, Finn JP, Brett E. Arch Ophthalmol 1990; 108: 812- 5 Gune). [ Reprint requests to Mr. D. Taylor, Department of Ophthalmology, The Hospitals for Sick Children, Great Ormond Street, London WCIN 3JH, England.] Three pediatric cases with symptoms of hemifacial spasm starting within weeks after birth up to 10 months after birth were found to have abnormalities on magnetic resonance scanning. One had apparent occlusion of the straight sinus with tortuous collateral veins, and two had intrinsic mass lesions compressing the fourth ventricle. The authors recommend investigation of any infant or pediatric cases of hemifacial spasm. Lyn A. Sedwick. M. D. Magnetic Resonance Imaging in Vogt- Koyanagi- Harada Syndrome. Arch OphthalmoI1990; 108: 783- 4 Gune). [ No reprint information given.] In this case report, a magnetic resonance orbital scan was useful in detecting bilateral choroidal thickening. Computerized tomographic scanning had suggested scleral thickening. Lyn A. Sedwick, M. D. Optic Disk Elevation in Down' Syndrome. Catalano RA, Simon JW. Am I OphthalmoI1990; 110: 2832 Guly). [ Reprint requests to Dr. R. A. Catalano, Albany Medical College, Department of Ophthalmology, 47 New Scotland Avenue, Albany, NY 12208.] The authors report on five children with Down' Syndrome, aged 1 month to 58 months, who had mild to moderate bilateral optic disk elevation without retinal or disk hemorrhage or vessel dilation. Some were studied with computerized tomographic brain scanning, and some had partial or complete resolution of disk edema over a period of time, with follow- up ranging from 6 to 41 months. No patient had lumbar puncture done. The authors discussed this curious finding, which they estimate to be present in 5% of the patients with Down' Syndrome seen in their clinic. It seems remarkable that the patients with disk elevation had no lumbar punctures performed and no ultrasound or computerized tomographic scanning of the orbits. Lyn A. Sedwick, M. D. Reversible Visual Loss in a Patient Receiving High- dose Ciprofloxacin Hydrochloride ( Cipro). Vrabec TR, Sergott RC, Jaeger EA, Savino PI, Bosley TM. Ophthalmology 1990; 97: 707- 10 Gune). [ Reprint requests to Dr. R. C. Sergott, Wills Eye Hospital, Ninth and Walnut Streets, Philadelphia, PA 19107.] The authors report a patient with sudden bilateral vision loss following 4 months of high- dose oral Cipro therapy for osteomyelitis. Examination and work- up suggested a toxic optic neuropathy, and after elimination of Cipro, the patient's vision gradually improved- but not to 100%. The authors feel that Cipro was the offending drug and cite its structural similarity to other quinoline- group compounds which are known to produce toxic optic neuropathies. Perhaps other case reports in the future will help to confirm this probable toxic effect of Cipro. Lyn A. Sedwick, M. D. Hydroxyamphetamine Mydriasis in Normal Subjects. Cremer SA, Thompson HS, Digre KB, Kardon RH. Am I Ophthalmol 1990; 110: 66- 70 Guly). [ Reprint requests to Dr. H. S. Thompson, Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242.] Hydroxyamphetamine Mydriasis in Horner's Syndrome. Cremer SA, Thompson HS, Digre KB, Kardon RH. Am I OphthalmoI1990; 110: 71- 6 Guly). 1Clin Neuro- ophthalmol. Vol. 11. No. 2, 1991 |
