| OCR Text |
Show 130 LITERATURE ABSTRACTS The authors use magnetic resonance to image the optic nerves of patients with unilateral or bilateral clinical optic nerve hypoplasia as well as normal controls. Magnetic resonance imaging clearly showed attenuation of signal in mild to severe optic nerve hypoplasia compared to normals, especially in coronal and axial views of the intracranial optic nerves. Given that other associated abnormalities may be detected ( i. e., absence of septum pellucidurn) and the sometimes difficult fundus examination of infants suspected of having optic nerve hypoplasia, magnetic resonance scanning may be a useful tool in distinguishing optic nerve hypoplasia from other causes of visual loss in infants. Lyn A. Sedwick, M. D. Graves' Ophthalmopathy: Correlation of Saccadic Eye Movements With Age, Presence of Optic Neuropathy, and Extraocular Muscle Volume. Feldon SE, Levin L, Liu SK. Arch Ophthalmol 1990; 108: 1568- 71 ( Nov). [ Reprint requests to Dr. S. E. Feldon, Doheny Eye Institute, 1355 San Pablo Street, Los Angeles, California 90033. J The authors use reflective infrared oculography to measure saccadic velocities in adduction of patients with Graves' disease and found a correlation between decreased velocity and development or already present optic neuropathy. They feel that this will be a " useful adjunct in evaluation of patients with Graves' ophthalmopathy" and believe it correlates with changes in extraocular muscle structure in these patients. Lyn A. Sedwick, M. D. Hydrogen Peroxide Localization in Experimental Optic Neuritis. Guy J, Ellis EA, Rao NA. Arch OphOwlmol 1990; 108: 1614- 21 ( Nov). [ Reprint requests to Dr. J. Guy, Neuro- Ophthalmology Service, Box J- 284, J. Hillis Miller Health Center, University of Florida, College of Medicine, Gainesville, FL 32610.] The authors report a hydrogen peroxide cesiumreaction- product can be found in the perivascular space in the optic nerve in animals with experimental allergic encephalitis. Many electron microZi?" hs are presented. The authors believe the re- 1CJinNeuro- ophllullmol. Vol ! 1 ,'.'.... 2. 1991 suits suggest that hydrogen peroxide " may playa role in the pathogenesis of altered vascular permeability in experimental optic neuritis." Lyn A. Sedwick, M. D. A Total Orbital Floor Fracture With Prolapse of the Globe Into the Maxillary Sinus Manifesting as Postenucleation Socket Syndrome. Smit T}, Koornneef L, Zonneveld FW. Am J Ophthalmol 1990; 110: 569- 70 ( Nov). [ Inquiries to Dr. T. J. Smit, Department of Ophthalmology, Orbital Center, A2- 1l8, Academisch Medisch Centrum, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. J This truly phenomenal case report involves a patient who sustained facial trauma from a windshield 6 years previously and purportedly had surgical removal of the right eye. He developed postenucleation socket symptoms, and work- up with computerized tomographic scanning showed total displacement of the right eye into the maxillary sinus. The computerized tomographic pictures are well worth a look. Lyn A. Sedwick, M. D. An Unusual Case of Neurosarcoidosis Confirmed by a Muscle Biopsy Specimen. Cheng KH, Brinkman CJ}' Rothova A. Am J Ophthalmol 1990; 110: 574- 5 ( Nov). [ Inquiries to Dr. C. J. J. Brinkman, Department of Ophthalmology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.] A patient with posterior uveitis and elevated angiotensin- converting enzyme and lysozyme levels had negative chest radiograph, gallium scanning, computerized tomographic, and magnetic resonance brain scanning findings. Lumbar puncture showed borderline elevated angiotensin- converting enzyme. A biopsy of the quadriceps femoris muscle disclosed noncaseating granulomas, thus establishing the presumed diagnosis of neurosarcoidosis. Lyn A. Sedwick, M. D. |
