Catastrophic Antiphospholipid Antibody Syndrome Manifesting as an Orbital Ischemic Syndrome

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Title Journal of Neuro-Ophthalmology, December 2001, Volume 21, Issue 4
Date 2001-12
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6md254v
Setname ehsl_novel_jno
ID 225101
Reference URL https://collections.lib.utah.edu/ark:/87278/s6md254v

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Title Catastrophic Antiphospholipid Antibody Syndrome Manifesting as an Orbital Ischemic Syndrome
Creator Vaphiades, MS; Brock, W; Brown, HH; Petursson, G; Westfall, CT
Affiliation Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205-7199, USA.
Abstract Painful bilateral ophthalmoparesis, marked proptosis, increased intraocular pressure, and blindness developed in a 29-year-old woman with protein C deficiency and catastrophic antiphospholipid syndrome. Magnetic resonance imaging of the orbits showed bilateral proptosis, globe tenting, and tethering of the optic nerves consistent with an orbital ischemic syndrome. Despite aggressive therapy for antiphospholipid syndrome, the patient died. The autopsy showed necrosis of orbital tissues. This is the first report of orbital ischemic syndrome from protein C deficiency and antiphospholipid syndrome.
Subject Adult; Antiphospholipid Syndrome/complications/diagnosis; Blindness/etiology; Exophthalmos/etiology; Fatal Outcome; Female; Humans; Intraocular Pressure; Ischemia/diagnosis/etiology; Magnetic Resonance Imaging; Ophthalmoplegia/etiology; Orbit/blood supply; Protein C Deficiency/complications/diagnosis; Syndrome
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 225084
Reference URL https://collections.lib.utah.edu/ark:/87278/s6md254v/225084