Vertical Saccades in Superior Oblique Palsy and Browns Syndrome

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Title Journal of Neuro-Ophthalmology, December 2001, Volume 21, Issue 4
Publisher Lippincott, Williams & Wilkins
Date 2001-12
Type Text
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
ARK ark:/87278/s6md254v
Setname ehsl_novel_jno
Date Created 2008-10-25
Date Modified 2020-03-03
ID 225101
Reference URL

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Title Vertical Saccades in Superior Oblique Palsy and Browns Syndrome
Creator Barton, JJ; Intriligator, JM
Affiliation Human Vision and Eye Movement Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
Subject Adult; Diagnostic Techniques, Ophthalmological; Female; Humans; Male; Middle Aged; Ocular Motility Disorders/physiopathology; Oculomotor Muscles/physiopathology; Ophthalmoplegia/physiopathology; Saccades/physiology; Syndrome
Abstract OBJECTIVE: To compare saccadic dynamics in superior oblique palsy and Brown's syndrome. METHODS: Vertical saccades in adduction and in abduction were studied in two subjects with superior oblique palsy and one with Brown's syndrome. Using large numbers of centrifugal saccades over a wide range of amplitudes, we measured peak velocity, duration, and the peak velocity/mean velocity ratio (PV/MV) as a function of saccadic amplitude. We compared vertical saccades in 30 degrees of abduction with those in 30 degrees of adduction. RESULTS: Superior oblique palsy caused a 15-18% reduction in peak velocities in adduction compared with abduction. Saccadic duration was also increased in adduction, with the result that there was no net change in the PV/MV ratio. In the patient with Brown's syndrome, velocities and durations of upward saccades were similar in abduction and adduction, but the PV/MV ratio was significantly elevated in adduction. We also observed an unusual high-speed lateral 'snap' of about 5 degrees that frequently interrupted vertical saccades in the midline but not elsewhere. CONCLUSION: Both paresis and restriction of the superior oblique alter vertical saccades. The effects of restriction on saccadic dynamics are distinct from the effects of paresis.
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Setname ehsl_novel_jno
Date Created 2008-10-25
Date Modified 2021-05-06
ID 225082
Reference URL