| Title |
Peripapillary Fluorescein Leakage in 11778 Lebers Optic Neuropathy |
| Creator |
Yen, MY; Wei, YH; Liu, JH |
| Affiliation |
Department of Ophthalmology, Taipei Veterans General Hospital, Taiwan, Republic of China. |
| Abstract |
A 17-year-old young man presented with a 2-month sequential visual loss in both eyes. Vision was 20/200 in the right eye and 20/400 in the left eye. Both discs were hyperemic with circumpapillary telangiectasia and nerve fiber swelling. Fluorescein angiography revealed a fuzzy hyperfluorescence due to leakage from dilated capillaries on both discs in the late transit. Molecular mitochondrial DNA study confirmed a homoplasmic 11778 Leber's optic neuropathy. |
| Subject |
Adolescent; Adult; Capillary Permeability; DNA, Mitochondrial/genetics; Female; Fluorescein; Fluorescein Angiography; Fluoresceins/metabolism; Fundus Oculi; Humans; Male; Optic Atrophies, Hereditary/diagnosis; Optic Atrophies, Hereditary/genetics; Optic Atrophies, Hereditary/physiopathology; Optic Disk/blood supply; Optic Nerve/pathology; Point Mutation; Retinal Vessels/metabolism; Retinal Vessels/pathology; Telangiectasis/pathology; Visual Acuity |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
224729 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6xw7qwv/224729 |
