Journal of Neuro-Ophthalmology, December 2013, Volume 33, Issue 4

Subretinal Abscess Causing Restricted Diffusion on Magnetic Resonance Imaging

Restricted diffusion of water molecules on diffusion-weighted magnetic resonance imaging most commonly associated with acute stroke, has also been described in brain abscess. It has been reported in only one case of sub-retinal abscess. Review of two cases. Two cases of visual loss from subretinal abscess had restricted diffusion in the region of the abscess. In the first case, DWI revealed restricted diffusion in a white mass visible in the posterior retina. In the second case, restricted diffusion was present in an anterior retinal mass invisible by ophthalmoscopy and ultrasound. In combination of restricted diffusion in the cerebrum consistent with septic emboli, these imaging abnormalities allowed earlier treatment that either preserved vision or prevented enucleation.