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MRI and Positron Emission Tomography Findings in Heidenhain Variant Creutzfeldt-Jakob Disease

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Title Journal of Neuro-Ophthalmology, September 2010, Volume 30, Issue 3
Date 2010-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6f79jm2
Setname ehsl_novel_jno
ID 227102
Reference URL https://collections.lib.utah.edu/ark:/87278/s6f79jm2

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Title MRI and Positron Emission Tomography Findings in Heidenhain Variant Creutzfeldt-Jakob Disease
Creator Prasad, Sashank; Lee, Edward B; Woo, John H; Alavi, Abass; Galetta, Steven L
Affiliation Departments of Neurology, University of Pennsylvania
Abstract The typical presentation of Heidenhain variant Creutzfeldt-Jakob disease (CJD) is a rapidly progressive visual loss in the setting of a relatively normal ophthalmologic examination. At presentation, patients with this uniformly fatal illness frequently demonstrate only minor cortical abnormalities on MRI. Here, we document the clinical presentation and imaging results of a patient with Heidenhain variant CJD in whom abnormalities on positron emission tomographic imaging were more evident than changes on MRI. These changes were present in striate cortex and visual association areas, providing clinical-anatomical correlation with our patient's visual deficits. Nuclear imaging provides a considerably more sensitive measure of neural dysfunction early in the course of this disease.
Subject Older people; Creutzfeldt-Jakob Syndrome; Female; Humans; Magnetic Resonance Imaging; Positron-Emission Tomography; Vision Disorders
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Setname ehsl_novel_jno
ID 227081
Reference URL https://collections.lib.utah.edu/ark:/87278/s6f79jm2/227081