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Show 150 LITERATURE ABSTRACTS volvement were found: Type I, in which retinal CMV infection marched toward the disc margin ( fairly good central vision was maintained, albeit with visual field defects after prompt antiviral therapy) and Type 2, in which papillitis and peripapillary retinitis were present from the onset and in which severe visual loss occurred despite antiviral therapy. Lyn A. Sedwick, M. D. Optic Glioma With Intraocular Tumor and Seeding in a Child with Neurofibromatosis. de Keizer RJW, de Wolff- Rouendaal 0, Bots GTAM, Thomeer RTWM, Brouwer OF, Vielvoye GJ. Am J Ophthalmol 1989; 108: 717- 25 ( Dec). [ Reprint requests to Dr. R. J. W. de Keizer, Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA Leiden, The Netherlands.] A 3- year- old boy with a progressive exophthalmos left eye was found to have an optic nerve glioma with intraocular tumor seeding. Sections of the optic nerve in the canal revealed malignant astrocytoma, grade 3, and other areas in the eye and nerve showed mitoses. The authors affirm the position that optic gliomas are true astrocytomas, not hamartomas, and may have characteristics ranging from benign to malignant. Lyn A. Sedwick, M. D. Trigeminal Schwannoma as a Cause of Chronic, Isolated Sixth Nerve Palsy. Del Priore LV, Miller NR. Am J Ophthalmol 1989; 108: 726- 9 ( Dec). [ Reprint requests to Dr. N. R. Miller, B107 Maumenee, Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore, MD 21205.] The authors report two patients with isolated sixth nerve palsy and initially negative neuroradiologic investigation who 4 and 8 years later developed fifth nerve findings and on repeat computerized tomographic ( CT) scanning had a mass in Meckel's cave surgically found to be schwannoma. Although the quality of the initial and follow- up CT scans might not have been comparable ( 1976 versus 1984, 1978 versus 1982), the authors note that, currently, magnetic resonance imaging probably would detect schwannoma of any size if attention were turned to the base of the skull and II} recommend that such a study be ordered for patients with isolated, unexplained chronic sixth nerve palsy. Lyn A. Sedwick, M. D. Syphilitic Uveitis in Human Immunodeficiency Virus- Infected and Noninfected Patients. Becerra LI, Ksiazek SM, Savino PJ, Marcus OK, Buckley RM, Sergott RC, Bosley TM. Ophthalmology 1989; 96: 1727- 30 ( Dec). [ Reprint requests to Dr. P. J. Savino, Neuro- Ophthalmology Service, Wills Eye Hospital, 9th and Walnut Sts., Philadelphia, PA 19107.] The authors report " the largest single series of patients . . . with luetic uveitis, associated with positive HIV testing." Cases were pulled from chart review from a uveitis clinic between 1986 and 1988, and aU had a positive VDRL. Of these 25 patients, 17 allowed testing for human immunodeficiency virus ( HIV), and 12 were positive. In general, ocular disease was more severe in patients who were HIV positive as well, but the numbers are relatively small. Lyn A. Sedwick, M. D. Bilateral Optic Nerve Compression as a Mechanism for the Foster Kennedy Syndrome. Watnick RL, Trobe JD. Ophthalmology 1989; 96: 1793- 8 ( Dec). [ Reprint request to Dr. J. D. Trobe, W. K. Kellogg Eye Center, 1000 Wall St., Ann Arbor, MI 48105- 1994. ] An ll- year- old child presented with unilateral visual loss and optic atrophy and normal vision with disc edema in the contralateral eye. A nasopharyngeal angiofibroma was found, which directly compressed both optic nerves without evidence of raised intracranial pressure, leading the authors to postulate that this case of " Foster Kennedy Syndrome" and perhaps others previously reported were the result solely of optic nerve compression and not unilateral compression and increased intracranial pressure, as originally espoused by Foster Kennedy to explain the findings. Their review of the literature supports several different mechanisms: Some cases did have evidence of unilateral compression and raised intracranial pressure, but others were simply bilateral optic |