Title |
Bilateral Optic Neuropathy Associated with Multiple Myeloma |
Creator |
Shimada, Y; Shibuya, M; Ohki, R; Yoneya, S; Nakamura, Y |
Affiliation |
Department of Ophthalmology, Saitama Medical School, Iruma, Saitama, Japan. ysmd@za2.so-net.ne.jp |
Abstract |
A 51-year-old man had reduced vision and bilateral optic disc swelling as the initial clinical manifestation of multiple myeloma. Brain imaging failed to disclose any abnormalities. Before any therapy was begun, visual function began to improve substantially. Three months after chemotherapy was started, visual function and optic disc appearance returned to near normal. There were no features to suggest polyneuropathy-organomegaly-endocrinopathy-M protein-skin changes (POEMS) syndrome. Visual loss in myeloma is usually caused by compression or infiltration of the optic nerves by tumor. The mechanism of the optic neuropathy in this case remains unknown. |
Subject |
Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Middle Older people; Multiple Myeloma, complications; Multiple Myeloma, diagnosis; Optic Nerve Diseases, diagnosis; Optic Nerve Diseases, etiology; Perimetry; Visual Acuity; Visual Fields |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
225568 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6hh9r4n/225568 |