| Title |
Pitfalls in the Diagnosis of Mitochondrial Encephalopathy with Lactic Acidosis and Stroke-Like Episodes |
| Creator |
Mizrachi, IB; Gomez-Hassan, D; Blaivas, M; Trobe, JD |
| Affiliation |
Department of Ophthalmology, W.K. Kellogg Eye Center, Ann Arbor, Michigan 48105, USA. |
| Abstract |
We describe a patient with genetically- and biochemically-proven mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) who was initially misdiagnosed as having had multiple ischemic strokes in part because the clinical presentation appeared to be acute, the MRI of lesions showed restricted diffusion, and the brain biopsy showed features suggestive of stroke. This report emphasizes the pitfalls in the diagnosis of MELAS and points out the similarities and differences between MELAS and ischemic stroke. |
| Subject |
Acidosis, Lactic, diagnosis; Adult; Biopsy; Brain, pathology; Diagnosis, Differential; Electroencephalography; Follow-Up Studies; Humans; Magnetic Resonance Imaging, methods; Male; Mitochondrial Encephalomyopathies, complications; Mitochondrial Encephalomyopathies, diagnosis; Stroke, diagnosis |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225547 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6n90gwz/225547 |
