| Title |
Neuro-Ophthalmologic Manifestations of Maffuccis Syndrome and Olliers Disease |
| Creator |
Balcer, LJ; Galetta, SL; Cornblath, WT; Liu, GT |
| Affiliation |
Department of Neurology, Hospital of the University of Pennsylvania, Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, USA. |
| Abstract |
Patients with Ollier's disease (multiple skeletal enchondromas) and Maffucci's syndrome (multiple enchondromas associated with subcutaneous hemangiomas) may develop skull base chondrosarcomas or low-grade astrocytomas as a delayed consequence of these disorders. We report three patients with Ollier's disease and Maffucci's syndrome who had diplopia as the initial manifestation of intracranial tumors. Since patients with Maffucci's syndrome and Ollier's disease are at risk for the delayed development of brain and systemic neoplasms, neuroophthalmologists must be aware of the need for long-term surveillance in patients affected by these conditions. |
| Subject |
Abducens Nerve/pathology; Adolescent; Adult; Astrocytoma/diagnosis; Brain/pathology; Brain Neoplasms/diagnosis; Chondrosarcoma/diagnosis; Cranial Nerve Diseases/diagnosis; Diplopia/diagnosis; Enchondromatosis/diagnosis; Facial Nerve/pathology; Facial Nerve Diseases/diagnosis; Female; Humans; Magnetic Resonance Imaging; Male; Paralysis/diagnosis; Skull/pathology; Skull Base Neoplasms/diagnosis; Trigeminal Nerve/pathology |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
224961 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6hm8fhh/224961 |
