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Show Journal ofNeiiro- Ophiluihiiohgy 19( 1): 39, 1999. © 1999 I. ippincoll Williams & Wilkins, Inc.. Philadelphia European Literature Abstracts H. Esriel Killer, M. D. Homonymous Hemianopsia as the Initial Manifestation of Multiple Sclerosis. Giindiiz K, Cansu K, Bul-duklar S, Saatci 1. Opthalmologica 1998; 212: 215- 20. [ Reprint requests to Kaan Giindiiz, M. D., G. M. K. Bul-vari 116/ 3, Maltepe 06570, Ankara ( Turkey).] Since the optic neuritis treatment trial, we learned a lot about visual field defects in optic neuritis, especially that there is no " typical" or pathognomonic field loss in this disease. Gundiiz et al. report an interesting case of a 28- year- old man in good health who manifested with a right homonymous hemianopsia. On magnetic resonance imaging ( MRI), a parietooccipital lesion that was compatible with the field defect was observed. This paper certainly enriches the differential diagnostic spectrum of homonymous hemianopsia. Clinicopathological Correlation of an Excised Choroidal Neovascular Membrane in Psuedotumour Cerebri. Castellarin AA, Sugino IK, Nasir M, Zarbin MA. Br J Ophthalmol 1997; 81: 994- 1000. [ Reprint requests to Marco A. Zarbin, M. D., Ph. D., University of Medicine and Dentistry, New Jersey Medical School, Department of Ophthalmology, 90 Bergen Street, 6lh floor, Newark, NJ 07103- 2499, U. S. A.] Choroidal neovascularization ( CNV) is a rare sequela of papilledema associated with benign intracranial hypertension. Only a few cases have been reported in the literature to date. This paper reports the case of a 32- year- old woman with pseudotumor cerebri who developed a CNV after longstanding papilledema. Because of severely decreased vision in the left eye due to the CNV, surgical excision of the CNV was performed. Histologically, the excised CNV disclosed hyperplastic retinal pigment epithelium, fibrovascular tissue, and no chorio-capillaris. Fluorescein angiography showed retinal pigment epithelium atrophy associated with choriocapillaris nonperfusion in the area of the dissected bed. The patient's vision did not improve. Optic Atrophy in Wolfram ( DIDMOAD) Syndrome. Barrett TG, Bundey SE, Fielder AR, Good PA. Eye 1997; 11: 882- 8. [ Reprint requests to Dr. T. G. Barrett, Clinical Genetics Unit, Birmingham Maternity Hospital, Edgbaston, Birmingham B15 2TG, UK.] Wolfram syndrome, also known as DIDMOAD ( Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), was studied in this paper using a nationwide cross- sectional case finding study. Forty- five patients were identified with an average age of 29 years. Optic atrophy was present in 38 patients with reduced visual acuity. The site of pathology and the pathogenesis of this rare entity are still unclear. Electroretinography and visual evoked potentials were deficient in most patients in this study. Magnetic resonance imaging of the brain showed generalized brain atrophy with reduced signals from the optic nerves and chiasm. A postmortem brain study showed atrophy of the optic nerves, chiasm, cerebellum, and brainstem. The authors conclude that optic atrophy in Wolfram syndrome may be caused by pathology in the optic nerve. Necrotising Fasciitis as a Complication of Botulinum Toxin Injection. Latimer PR, Hodgkins PR, Vakalis AN, Butler RE, Evans AR. Eye 1998; 12: 51- 3. [ Reprint requests to P. R. Latimer, Department of Ophthalmology, St George's Hospital, Blackshaw Road, London SWI7 0QT, UK.] Botulinum toxin is considered the safe first line medication for essential blepharospasm and hemifacial spasm. Complications, such as tearing, diplopia, and upper lid ptosis, are rare and usually transient. A necrotizing fasciitis as reported in this paper is certainly a very rare complication in a patient with deficiency of the immune system caused by chronic myeloid leukemia. 39 |
