Title |
Visual Loss with Langerhans Cell Histiocytosis |
Creator |
Job, OM; Schatz, NJ; Glaser, JS |
Affiliation |
Department of Neuro-Ophthalmology, Mercy Neuro-Science Institute, Miami, Florida 33133, USA. |
Abstract |
A 42-year-old woman with a 6-year history of diabetes insipidus and progressive hypersomnolence presented with visual loss. Neuroimaging showed infiltration in the hypothalamus, the optic nerve, and the chiasm, as well as multiple lesions in other areas of the brain parenchyma. Biopsy showed Langerhans cell histiocytosis. This is an unusual presentation of Langerhans cell histiocytosis, involving the visual pathways without manifestations outside of the central nervous system. The differential diagnosis and the magnetic resonance imaging findings will be discussed. |
Subject |
Administration, Oral; Adult; Brain Diseases/complications/diagnosis/drug therapy; Female; Histiocytosis, Langerhans-Cell/complications/diagnosis/drug therapy; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Methylprednisolone/therapeutic use; Optic Chiasm/pathology; Optic Nerve/pathology; Prednisone/therapeutic use; Vision Disorders/diagnosis/drug therapy/etiology; Visual Acuity; Visual Fields; Visual Pathways/pathology |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
224958 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6hm8fhh/224958 |