| Title |
Early Diagnosis of Horner Syndrome Using Topical Apraclonidine |
| Creator |
Cooper-Knock, Jonathan; Pepper, Irene; Hodgson, Timothy; Sharrack, Basil |
| Affiliation |
Department of Neurology, Sheffield Teaching Hospitals NHS Trust, University of Sheffield, Sheffield, United Kingdom |
| Abstract |
The diagnosis of Horner syndrome (HS) using apraclonidine eye drops is an alternative to the use of topical cocaine drops. A number of reports have described the efficacy of apraclonidine testing, but there is some debate over its sensitivity in the acute setting. We describe a patient with HS secondary to carotid dissection who had a positive response to apraclonidine 3 hours after the onset of symptoms. The case is made for a larger study of apraclonidine use to determine its true sensitivity and specificity, identify confounding factors, and redefine the criteria for positive testing. |
| Subject |
Administration, Topical; Adrenergic alpha-2 Receptor Agonists/administration & dosage; Adrenergic alpha-2 Receptor Agonists/diagnostic use; Adult; Anisocoria/diagnosis; Anisocoria/etiology; Anisocoria/physiopathology; Carotid Artery, Internal, Dissection/complications; Carotid Artery, Internal, Dissection/pathology; Carotid Artery, Internal, Dissection/radiography; Clonidine/administration & dosage; Clonidine/analogs & derivatives; Clonidine/diagnostic use; Early Diagnosis; Horner Syndrome/diagnosis; Horner Syndrome/etiology; Horner Syndrome/physiopathology; Humans; Iris/drug effects; Iris/innervation; Iris/physiopathology; Male |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
227200 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6pk3n9m/227200 |
