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Optic Pathway Gliomas

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Title Journal of Neuro-Ophthalmology, September 2011, Volume 31, Issue 3
Date 2011-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6pk3n9m
Setname ehsl_novel_jno
ID 227219
Reference URL https://collections.lib.utah.edu/ark:/87278/s6pk3n9m

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Title Optic Pathway Gliomas
Creator Avery, Robert A; Fisher, Michael J; Grant T. Liu, MD. Professor of Neurology, University of Pennsylvania
Affiliation Department of Neurology, Children's National Medical Center, Washington, District of Columbia
Abstract Childhood optic pathway gliomas (OPGs) are low-grade neoplasms intrinsic to the optic nerve, optic chiasm, tracts, and radiations. The management of OPGs is still a highly controversial topic among neuro-ophthalmologists. Authors' personal experience and literature review.This review describes our current understanding of the behavior of OPGs and discusses advances in their imaging, evaluation, and management. Patients with OPGs that progress are typically treated with chemotherapy using carboplatin and vincristine; however, newer approaches to therapy are being explored.Although chemotherapy is the mainstay of treatment when indicated, multicenter collaborative studies involving oncologists and neuro-ophthalmologists, both retrospective and prospective, are still needed to establish evidence-based guidelines for the management of children with OPGs.
Subject Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Brain Neoplasms/drug therapy; Brain Neoplasms/pathology; Child, Preschool; Female; Glioma/drug therapy; Glioma/pathology; Humans; Neoplasm Invasiveness/pathology; Neoplasm Invasiveness/prevention & control; Neoplasm Staging/methods; Neural Pathways/drug effects; Neural Pathways/pathology; Optic Nerve Neoplasms/drug therapy; Optic Nerve Neoplasms/pathology
OCR Text Show
Format application/pdf
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Setname ehsl_novel_jno
ID 227213
Reference URL https://collections.lib.utah.edu/ark:/87278/s6pk3n9m/227213