Optic pathway gliomas: a review

Update item information
Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Kestle, John R. W.; Brockmeyer, Douglas Lee
Other Author Binning, Mandy J.; Liu, James K.; Walker, Marion L.
Title Optic pathway gliomas: a review
Date 2007
Description Optic pathway gliomas represent approximately 3-5% of childhood intracranial tumors. They usually occur in children during the first decade of life and are seen in 11-30% of patients with neurofibromatosis Type 1 (NF1). Although these tumors are typically low-grade gliomas, the clinical course and natural history are highly variable, making treatment paradigms difficult. Overall, however, they are often indolent tumors that can be observed over time for progression without initial treatment, especially in patients with NF1. Chemotherapy is the first-line treatment for progressive tumors, and radiation therapy is reserved for patients with progressive disease who are older than 5-7 years. Surgery is reserved for large tumors causing mass effect or hydrocephalus and tumors confined to the orbit or unilateral optic nerve.
Type Text
Publisher American Association of Neurological Surgeons (AANS)
Volume 23
Issue 5
First Page 1
Last Page 8
Subject Optic pathway glioma; Hypothalamus glioma; Neurofibromatosis Type 1
Subject LCSH Gliomas; Neurofibromatosis; Pediatric neurology
Language eng
Bibliographic Citation Binning, M. J., Liu, J. K., Kestle, J. R. W., Brockmeyer, D. L., & Walker, M. L. (2007). Optic pathway gliomas: a review. Neurosurgical Focus, 23(5), E2, 1-8.
Rights Management (c) American Association of Neurological Surgeons
Format Medium application/pdf
Format Extent 255,040 bytes
Identifier ir-main,13237
ARK ark:/87278/s6rj52rf
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2013-02-21
ID 703955
Reference URL https://collections.lib.utah.edu/ark:/87278/s6rj52rf
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