Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

Update Item Information
Publication Type Journal Article
School or College College of Science
Department Biology
Creator Beckerle, Mary C.; Yoshigi, Masaaki; Hoffman, Laura M.; Yost, H. Joseph
Other Author Jensen, Christopher C.
Title Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement
Date 2005
Description Organs and tissues adapt to acute or chronic mechanical stress by remodeling their actin cytoskeletons. Cells that are stimulated by cyclic stretch or shear stress in vitro undergo bimodal cytoskeletal responses that include rapid reinforcement and gradual reorientation of actin stress fibers; however, the mechanism by which cells respond to mechanical cues has been obscure.
Type Text
Publisher Rockefeller University Press
Volume 171
Issue 2
First Page 209
Last Page 215
Subject Zyxin; Actin
Subject LCSH Phosphoproteins; Cytoskeletal proteins; Protein-protein interactions; Cytoskeleton; Cell physiology; Stress (Physiology)
Language eng
Bibliographic Citation Yoshigi, M., Hoffman, L. M., Jensen, C. C., Yost, H. J., & Beckerle, M. C. (2005). Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement. Journal of Cell Biology, 171(2), 209-15.
Rights Management (c) Yoshigi, M., Hoffman, L. M., Jensen, C. C., Yost, H. J., & Beckerle, M. C. 2005. Originally published in J. Cell Biol. 171(2), 209-15. http://creativecommons.org/licenses/by-nc-sa/3.0/
Format Medium application/pdf
Format Extent 1.191,352 bytes
Identifier ir-main,6609
ARK ark:/87278/s68k7t47
Setname ir_uspace
ID 702223
Reference URL https://collections.lib.utah.edu/ark:/87278/s68k7t47
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