Title |
Neuro-Ophthalmological Features of Primary Diffuse Leptomeningeal Gliomatosis |
Creator |
Noval, Susana; Ortiz-Perez, Santiago; Sanchez-Dalmau, Bernardo F; Ruiz-Ares, Gerardo; Arpa, Javier; Sadun, Alfredo |
Affiliation |
Department of Ophthalmology, Hospital University La Paz, Madrid, Spain |
Abstract |
We performed an in-depth study of the neuro-ophthalmologic signs and symptoms of a rare but fatal disease known as primary diffuse leptomeningeal gliomatosis (PDLG). Two new cases of PDLG are described, and 22 published cases reviewed. Papilledema and sixth nerve palsy are the most common neuro-ophthalmic findings. Other abnormalities include third and fourth nerve palsies, nystagmus, and vision loss. Involvement of the visual system may be part of the initial presentation of PDLG. |
Subject |
Abducens Nerve Diseases; Adolescent; Antitubercular Agents; Cerebrospinal Fluid Pressure; Cranial Irradiation; Fatal Outcome; Female; Humans; Magnetic Resonance Imaging; Neoplasms, Neuroepithelial; Neoplasms, Neuroepithelial; Papilledema; Tuberculosis, Meningeal; Tuberculosis, Meningeal; Vision Disorders; Visual Acuity; Young Adult |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
227222 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6jx1m0m/227222 |