| Title |
Magnetic Resonance Findings in the Pregeniculate Visual Pathways in Leber Hereditary Optic Neuropathy |
| Creator |
van Westen, Danielle; Hammar, Bjorn; Bynke, Gunnel |
| Affiliation |
Department of Neuroradiology, Center for Medical Imaging and Physiology, Skne University Hospital, and Department of Diagnostic Radiology, Lund University, Lund, Sweden |
| Abstract |
Two relatives, a 61-year-old man and the 21-year-old grandson of his sister, suffered from bilateral visual loss and were diagnosed with Leber hereditary optic neuropathy. In both cases, the diagnosis was molecularly confirmed with the 11778 mitochondrial mutation. MRI showed increased T2 signal not only in the optic nerves and chiasm but also in the optic tracts, extending to the lateral geniculate bodies. To our knowledge, the latter finding has not been described previously. |
| Subject |
Autonomic Fibers, Preganglionic; Genetic Predisposition to Disease; Humans; Magnetic Resonance Imaging; Male; Middle Older people; Optic Atrophy, Hereditary, Leber; Optic Nerve; Visual Pathways; Young Adult |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
227133 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s65t6rms/227133 |
