| Title |
Axonal Degeneration in Peripheral Nerves in a Case of Leber Hereditary Optic Neuropathy |
| Creator |
Mnatsakanyan, Lilit; Ross-Cisneros, Fred N; Carelli, Valerio; Wang, Michelle Y; Sadun, Alfredo A |
| Affiliation |
Doheny Eye Institute, Department of Ophthalmology, University of Southern California |
| Abstract |
Leber hereditary optic neuropathy (LHON) is a mitochondrial DNA (mtDNA) genetic disorder characterized by profound bilateral loss of central vision due to selective loss of retinal ganglion cells. Most patients with LHON do not have complaints related to the peripheral nervous system. We investigated possible qualitative and quantitative histological changes in the peripheral nerve of a patient with LHON as compared to normal controls. |
| Subject |
Older people; Brachial Plexus Neuropathies; Disease Progression; Female; Humans; Optic Atrophy, Hereditary, Leber; Peripheral Nervous System Diseases; Wallerian Degeneration |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
227124 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s65t6rms/227124 |
