Optic neuritis or ophthalmic artery aneurysm? Case presentation with histopathologic documentation utilizing a new staining method.

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Title Journal of Neuro-Ophthalmology, December 1984, Volume 4, Issue 4
Publisher Lippincott, Williams & Wilkins
Date 1984-12
Type Text
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
ARK ark:/87278/s6df9x9b
Setname ehsl_novel_jno
Date Created 2011-01-12
Date Modified 2020-03-03
ID 226802
Reference URL https://collections.lib.utah.edu/ark:/87278/s6df9x9b

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Title Optic neuritis or ophthalmic artery aneurysm? Case presentation with histopathologic documentation utilizing a new staining method.
Creator Sadun, A.A.; Smythe, B.A.; Schaechter, J.D.
Subject Aged; Aneurysm; Diagnosis, Differential; Female; Fundus Oculi; Geniculate Bodies; Humans; Nerve Degeneration; Ophthalmic Artery; Optic Nerve; Optic Neuritis; Phenylenediamines
Abstract An elderly woman was admitted to the hospital with a presumptive diagnosis of optic neuritis following abrupt loss of vision in her left eye. Noninvasive studies were unrevealing, and she was put on a course of prednisone. Further visual loss 2 weeks later prompted a second course of prednisone therapy. Six years later the patient died from cardiac arrest. The autopsy revealed an aneurysm arising from the origin of the left ophthalmic artery. Selected brain specimens were histologically examined by application of a newly developed staining technique capable of identifying degenerated axons in human brain tissue even after long survival periods. We traced degeneration from the site of compression at the left optic nerve to five primary visual nuclei. Furthermore, transsynaptic cellular changes were observed in the lateral geniculate nucleus.
OCR Text Show
Publisher Lippincott, Williams & Wilkins
Date 1984-12
Type Text
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
Setname ehsl_novel_jno
Date Created 2011-01-12
Date Modified 2011-01-12
ID 226797
Reference URL https://collections.lib.utah.edu/ark:/87278/s6df9x9b/226797