Title |
The Fisher variant of Guillain-Barr syndrome (Fisher syndrome). |
Creator |
Snyder, Lee A; Rismondo, Vivian; Miller, Neil R |
Affiliation |
Wilmer Eye Institute, Johns Hopkins Hospital, Owings Mills, Maryland, USA |
Abstract |
Fisher syndrome (FS) is an acute polyneuropathy typically characterized by the triad of ataxia, areflexia, and ophthalmoplegia, although it may present with 2 or even just 1 of these clinical findings. Similarities between FS and other acute polyneuropathies such as Guillain-Barr syndrome (GBS) and Bickerstaff brainstem encephalitis (BBE) suggest that FS is part of a spectrum of autoimmune disorders that may affect the peripheral and/or central nervous system. Anti-GQ1b antibody is present in the serum of more than 85% of patients with FS, but it is not specific to FS. Why some patients develop FS and others develop typical GBS or one of its other variants is still largely unknown. |
Subject |
Ataxia; Biological Markers; Disease Progression; Humans; Incidence; Miller Fisher Syndrome; Ophthalmoplegia |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
226369 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6vm7jb7/226369 |