| Title |
Evidence for a metabolic trigger for Leber's hereditary optic neuropathy. A case report. |
| Creator |
DuBois, L.G.; Feldon, S.E. |
| Affiliation |
Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles. |
| Abstract |
A 9-year-old girl with recently diagnosed juvenile onset diabetes mellitus presented with signs and symptoms of bilateral optic neuropathy. Leber's hereditary optic neuropathy was suspected on the basis of a strong family history. Subsequent mitochondrial DNA testing was positive. Visual recovery occurred once the diabetes was well controlled. This case suggests that such metabolic compromise that occurs in diabetes may precipitate the clinical expression of Leber's optic neuropathy. |
| Subject |
Child; DNA Mutational Analysis; DNA, Mitochondrial; Diabetes Mellitus, Type 1; Female; Humans; Optic Atrophies, Hereditary; Visual Acuity |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
226050 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6j99cgt/226050 |
