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Restricted diffusion in the optic nerve and retina demonstrated by MRI in rhino-orbital mucormycosis.

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Title Journal of Neuro-Ophthalmology, March 2009, Volume 29, Issue 1
ARK ark:/87278/s6tt7x2z
ID 225836
setname ehsl_novel_jno

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Title Restricted diffusion in the optic nerve and retina demonstrated by MRI in rhino-orbital mucormycosis.
Creator Hatipoglu, Hatice Gul; Gurbuz, Muge Onbasioglu; Yuksel, Enis
Affiliation Department of Radiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Subject Adult; Blindness; Cavernous Sinus Thrombosis; Diffusion Magnetic Resonance Imaging; Eye Infections, Fungal; Fatal Outcome; Humans; Male; Mucormycosis; Optic Nerve; Orbital Cellulitis; Paranasal Sinus Diseases; Retina
Abstract A 29-year-old man developed vision loss in the right eye due to ophthalmic artery, cavernous sinus, and superior ophthalmic vein occlusion in mucormycosis. Diffusion MRI obtained within 2 days of symptom onset showed that the apparent diffusion coefficient values of the optic nerve and retina were remarkably decreased on the affected compared with the unaffected side. A follow-up MRI study 21 days after symptom onset revealed the anticipated disappearance of these signal changes, confirming that they were a true reflection of ischemia in the optic nerve and retina. This report adds to an accumulating body of literature on restricted diffusion in these tissues in conditions producing severe ischemia.
Publisher Lippincott, Williams & Wilkins
Date 2009-03
Type Text
Rights Management North American Neuro-Ophthalmology Society
Publication Type Journal Article
ID 225819
setname ehsl_novel_jno