| Title |
Primary Sinonasal Undifferentiated Carcinoma Presenting with Bilateral Retrobulbar Optic Neuropathy |
| Creator |
Tamhankar, M. A.; Volpe, N. J.; Loevner, L. A.; Palmer, J. N.; Feldman, M. |
| Affiliation |
Division of Neuro-ophthalmology, Scheie Eye Institute, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, 51 North 39th Street, Philadelphia, PA 19104, USA. |
| Abstract |
A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm. |
| Subject |
Adult; Antineoplastic Combined Chemotherapy Protocols, therapeutic use; Biopsy; Carcinoma, complications; Carcinoma, pathology; Carcinoma, physiopathology; Cranial Fossa, Anterior, pathology; Cranial Fossa, Anterior, physiopathology; Fatal Outcome; Functional Laterality; Humans; Magnetic Resonance Imaging; Male; Nasal Cavity, pathology; Nasal Cavity, physiopathology; Neoplasm Metastasis, pathology; Optic Nerve, pathology; Optic Nerve, physiopathology; Optic Nerve Diseases, etiology; Optic Nerve Diseases, pathology; Optic Nerve Diseases, physiopathology; Orbit, pathology; Orbit, physiopathology; Paranasal Sinus Neoplasms, complications; Paranasal Sinus Neoplasms, pathology; Paranasal Sinus Neoplasms, physiopathology; Paranasal Sinuses, pathology; Paranasal Sinuses, physiopathology; Radiotherapy; Treatment Failure; Tumor Markers, Biological; Vision, Low, etiology; Vision, Low, pathology; Vision, Low, physiopathology |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225609 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s68087qb/225609 |
