| Title |
Optic Disc Edema, Cystoid Macular Edema, and Elevated Vascular Endothelial Growth Factor in a Patient with POEMS Syndrome |
| Creator |
Chong, DY; Comer, GM; Trobe, JD |
| Affiliation |
Department of Ophthalmology, W. K. Kellogg Eye Center, University of Michigan, 1000 Wall Street, Ann Arbor, MI 48105, USA. |
| Abstract |
A 48-year-old man with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome had bilateral optic disc edema (ODE), bilateral cystoid macular edema (CME), anasarca, and elevated serum vascular endothelial growth factor (VEGF). This is the first reported example of ophthalmoscopic, angiographic, and optical coherence tomographic evidence of the combination of ODE and CME in this syndrome. This combination of features suggests that the ODE in this condition may be due to increased vascular permeability. |
| Subject |
Biological Markers, analysis; Biological Markers, blood; Fatal Outcome; Humans; Interleukin-6, blood; Macula Lutea, pathology; Macula Lutea, physiopathology; Macular Edema, blood; Macular Edema, etiology; Macular Edema, physiopathology; Male; Middle Older people; Optic Disk, pathology; Optic Disk, physiopathology; POEMS Syndrome, complications; POEMS Syndrome, physiopathology; Papilledema, blood; Papilledema, etiology; Papilledema, physiopathology; Retinal Artery, pathology; Retinal Artery, physiopathology; Tomography, Optical Coherence; Up-Regulation, physiology; Vascular Endothelial Growth Factor A, blood |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225607 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s68087qb/225607 |
