| Title |
Erectile Dysfunction Drugs and Non-Arteritic Anterior Ischemic Optic Neuropathy |
| Creator |
Hayreh, SS |
| Affiliation |
Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. sohan-hayreh@uiowa.edu |
| Abstract |
The recent reports of non-arteritic anterior ischemic optic neuropathy (NAION) occurring shortly after ingestion of erectile dysfunction agents have raised the question of whether these agents have a cause-and-effect relationship to NAION. The nature of optic nerve head blood flow and the various factors that influence it, the systemic vascular effects of these agents, and the clinical features of NAION lead me to believe that these agents are contributory factors. Patients with the appropriate risk factors should, therefore, be warned of this possibility and advised to refrain from using these agents. |
| Subject |
3',5'-Cyclic-GMP Phosphodiesterases, antagonists & inhibitors; Carbolines, adverse effects; Erectile Dysfunction, drug therapy; Humans; Imidazoles, adverse effects; Male; Optic Disk, blood supply; Optic Neuropathy, Ischemic, chemically induced; Phosphodiesterase; Inhibitors, adverse effects; Piperazines, adverse effects; Purines; Risk Factors; Sulfones, adverse effects; Triazines, adverse effects |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225487 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s61g3sbs/225487 |
