| Title |
Primary Melanoma of the Sphenoid Sinus Presenting with a Third Cranial Nerve Palsy |
| Creator |
Lynch, SC; Lee, AG; Graham, SM; Kirby, PA |
| Affiliation |
Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA. |
| Abstract |
An 83-year-old woman presented with right trigeminal paresthesias, upper lid ptosis, and diplopia and was found to have a right third cranial nerve palsy. MRI disclosed a right sphenocavernous mass with speckled high signal on pre-contrast T1 and correspondingly low signal on T2. Endoscopic sphenoidotomy revealed malignant melanoma. The patient underwent radiation therapy with complete and protracted resolution of the palsy. An extensive evaluation for a primary source was negative. The combination of high T1 signal and low T2 signal in a mass should suggest melanin. An exceedingly rare condition, this is the first English report of its presentation with a third cranial nerve palsy. |
| Subject |
Older people, 80 and over; Blepharoptosis, diagnosis; Diplopia, diagnosis; Female; Humans; Magnetic Resonance Imaging; Melanoma, pathology; Oculomotor Nerve Diseases, diagnosis; Paranasal Sinus Neoplasms, pathology; Sphenoid Sinus, pathology; Tomography, X-Ray Computed |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225485 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s61g3sbs/225485 |
