| Title |
Interferon-alpha-Associated Bilateral Simultaneous Ichemic Optic Neuropathy |
| Creator |
Vardizer, Y; Linhart, Y; Loewenstein, A; Garzozi, H; Mazawi, N; Kesler, A |
| Affiliation |
Department of Ophthalmology, Tel Aviv Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel. |
| Abstract |
The authors describe one patient with essential thrombocytosis and one with chronic hepatitis C infection who developed bilateral simultaneous anterior ischemic optic neuropathy within 3 months of starting treatment with interferon-alpha. One patient had several typical risk factors for conventional AION; the other did not. These cases are the fourth and fifth reported examples of this phenomenon. Interferon-alpha treatment may cause or aggravate the risk of developing anterior ischemic optic neuropathy. Vulnerable patients should be advised of this potential complication, assisted in reducing risk factors, and monitored for optic nerve and retinal vascular complications. |
| Subject |
Adult; Antiviral Agents/adverse effects; Fundus Oculi; Hepatitis C, Chronic/drug therapy; Humans; Interferon-alpha/adverse effects; Male; Middle Older people; Optic Neuropathy, Ischemic/chemically induced; Optic Neuropathy, Ischemic/pathology; Optic Neuropathy, Ischemic/physiopathology; Thrombocytosis/drug therapy; Visual Fields/drug effects |
| Date |
1994-06 |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225311 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s62g0thm/225311 |
