| Title |
Whipple Disease with Supranuclear Ophthalmoplegia Diagnosed by Polymerase Chain Reaction of Cerebrospinal Fluid |
| Creator |
Andrew G. Lee |
| Affiliation |
Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA. |
| Abstract |
An elderly man developed acute progressive supranuclear ophthalmoplegia and other central nervous system manifestations that suggested Whipple disease. Results of small intestinal biopsy were negative but polymerase chain reaction testing of the cerebrospinal fluid confirmed the diagnosis. |
| Subject |
Actinobacteria/genetics/isolation & purification; Older people; Anti-Bacterial Agents; Cerebrospinal Fluid/microbiology; Drug Therapy, Combination/therapeutic use; Fatal Outcome; Humans; Magnetic Resonance Imaging; Male; Polymerase Chain Reaction; RNA, Bacterial/analysis; Supranuclear Palsy, Progressive/cerebrospinal fluid/diagnosis; Trimethoprim-Sulfamethoxazole Combination/therapeutic use; Whipple Disease/cerebrospinal fluid/diagnosis |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225238 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6kh3tcz/225238 |
