Title |
A Case of Bilateral Optic Neuropathy and Recurrent Transverse Myelopathy Associated with Perinuclear Anti-Neutrophil Cytoplasmic Antibodies |
Creator |
Harada, T; Ohashi, T; Harada, C; Yoshida, K; Maguchi, S; Moriwaka, F; Matsuda, H |
Affiliation |
Department of Ophthalmology, Hokkaido University School of Medicine, Sapporo, Japan. |
Abstract |
A case involving a 52-year-old man having bilateral optic neuropathy and recurrent transverse myelopathy is reported. His clinical features resembled multiple sclerosis, but neuroimaging failed to show evidence of demyelination or inflammation in the brain or the optic nerves. The patient experienced sudden visual loss despite massive steroid therapy. Positive perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) is suggestive that optic neuropathy and recurrent transverse myelopathy may have been caused by some common inflammatory processes associated with p-ANCA, however, having a different etiology from multiple sclerosis. |
Subject |
Antibodies, Antineutrophil Cytoplasmic/blood; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Middle Older people; Multiple Sclerosis/diagnosis; Myelitis, Transverse/diagnosis; Myelitis, Transverse/immunology; Optic Neuropathy, Ischemic/diagnosis; Optic Neuropathy, Ischemic/immunology; Recurrence |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
224892 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6wx0pr1/224892 |