| Title |
Bilateral Anterior Ischemic Optic Neuropathy Following Influenza Vaccination |
| Creator |
Kawasaki, A; Purvin, VA; Tang, R |
| Affiliation |
Midwest Eye Institute, Indianapolis, IN 46280, USA. |
| Abstract |
Optic neuritis is an occasional complication of vaccination. Visual loss can be unilateral or bilateral, and most patients recover substantially without treatment. The presumptive mechanism is an immune-mediated demyelinating injury of the optic nerve. We report two patients who had permanent visual loss following influenza vaccination. Their pattern of visual loss, segmental optic disc changes, and failure of visual recovery were atypical for demyelinating optic neuritis and reminiscent of a primary ischemic injury to the optic nerve. We speculate that an immune complex-mediated vasculopathy following vaccination can cause anterior ischemic optic neuropathy. Clinicians should be aware of this entity because of the less favorable prognosis for visual recovery in these cases. |
| Subject |
Blindness/etiology; Female; Fundus Oculi; Humans; Influenza Vaccines/adverse effects; Middle Older people; Optic Atrophy/etiology; Optic Disk/pathology; Optic Neuropathy, Ischemic/etiology; Optic Neuropathy, Ischemic/pathology; Papilledema/etiology; Papilledema/pathology; Vaccination/adverse effects; Visual Acuity; Visual Fields |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
224879 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s61p1668/224879 |
