Bilateral Anterior Ischemic Optic Neuropathy Following Influenza Vaccination

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Title Journal of Neuro-Ophthalmology, March 1998, Volume 18, Issue 1
Date 1998-03
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s61p1668
Setname ehsl_novel_jno
ID 224883
Reference URL https://collections.lib.utah.edu/ark:/87278/s61p1668

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Title Bilateral Anterior Ischemic Optic Neuropathy Following Influenza Vaccination
Creator Kawasaki, A; Purvin, VA; Tang, R
Affiliation Midwest Eye Institute, Indianapolis, IN 46280, USA.
Abstract Optic neuritis is an occasional complication of vaccination. Visual loss can be unilateral or bilateral, and most patients recover substantially without treatment. The presumptive mechanism is an immune-mediated demyelinating injury of the optic nerve. We report two patients who had permanent visual loss following influenza vaccination. Their pattern of visual loss, segmental optic disc changes, and failure of visual recovery were atypical for demyelinating optic neuritis and reminiscent of a primary ischemic injury to the optic nerve. We speculate that an immune complex-mediated vasculopathy following vaccination can cause anterior ischemic optic neuropathy. Clinicians should be aware of this entity because of the less favorable prognosis for visual recovery in these cases.
Subject Blindness/etiology; Female; Fundus Oculi; Humans; Influenza Vaccines/adverse effects; Middle Older people; Optic Atrophy/etiology; Optic Disk/pathology; Optic Neuropathy, Ischemic/etiology; Optic Neuropathy, Ischemic/pathology; Papilledema/etiology; Papilledema/pathology; Vaccination/adverse effects; Visual Acuity; Visual Fields
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Format application/pdf
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Setname ehsl_novel_jno
ID 224879
Reference URL https://collections.lib.utah.edu/ark:/87278/s61p1668/224879