Myelin Oligodendrocyte Glycoprotein (MOG) - Antibody Optic Neuritis

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Identifier EEC-MOG-NOVEL
Title Myelin Oligodendrocyte Glycoprotein (MOG) - Antibody Optic Neuritis
Creator Bryce Buchowicz, MD; Valérie Biousse, MD
Affiliation (BB) Neuro-ophthalmology Fellow, Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia; (VB) Cyrus H. Stoner Professor of Ophthalmology, Professor of Ophthalmology and Neurology, Departments of Ophthalmology and Neurology, Emory University School of Medicine, Atlanta, Georgia
Subject Myelin Oligodendrocyte Glycoprotein (MOG)-antibody; MOG-ab
Description This is an illustrated guide to the clinical diagnosis of myelin oligodendrocyte glycoprotein (MOG)-antibody optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein on the surface of myelin and is found exclusively in the central nervous system (CNS). MOG likely mediates a complement cascade which causes an inflammatory demyelinating condition of the CNS. It can occur at any age with median onset in the 4th decade. It can be monophasic or often relapsing. The most common presenting feature is optic neuritis. It is frequently associated with bilateral with optic nerve head edema. MRI will commonly show optic nerve sheath enhancement. MOG optic neuritis has better visual outcomes than neuromyelitis optica (NMO), although relapses may be more frequent. MOG commonly causes myelitis or acute disseminated encephalomyelitis (ADEM) in children.
Date 2020-06
Language eng
Format application/pdf
Format Creation Microsoft PowerPoint
Type Text
Collection Neuro-Ophthalmology Virtual Education Library - The Emory Eye Center Neuro-Ophthalmology Collection: https://novel.utah.edu/eec/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Rights Management Copyright 2002. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6fn6q76
Setname ehsl_novel_eec
ID 1571530
Reference URL https://collections.lib.utah.edu/ark:/87278/s6fn6q76
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