Intracranial malignancies occurring more than 20 years after radiation therapy for pituitary adenoma.

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Title Journal of Neuro-Ophthalmology, December 2009 Volume 29, Issue 4
Date 2009-12
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6vm7jb7
Setname ehsl_novel_jno
ID 226379
Reference URL https://collections.lib.utah.edu/ark:/87278/s6vm7jb7

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Title Intracranial malignancies occurring more than 20 years after radiation therapy for pituitary adenoma.
Creator Wu-Chen, Wen Ying; Jacobs, Dina A; Volpe, Nicholas J; Dalmau, Joseph O; Moster, Mark L
Affiliation Department of Neurology, Temple University Hospital, Philadelphia, Pennsylvania, USA.
Abstract A 37-year-old woman developed a left third cranial nerve palsy 28 years after radiation for a nonsecreting pituitary adenoma. Imaging disclosed a left parasellar mass and a midbrain/pontine signal abnormality. Biopsy of the parasellar mass revealed a malignant sarcoma. The brainstem abnormality was presumptively diagnosed as a malignant glioma. A 63-year-old man developed a malignant astrocytoma of the left optic nerve and chiasm 23 years after partial excision and radiation of a nonsecreting pituitary adenoma. Both patients died of their malignancies. Although secondary malignancies have been described in this setting, such long latencies have not been reported.
Subject Adenoma; Adult; Brain Stem Neoplasms; Fatal Outcome; Female; Glioma; Humans; Male; Middle Older people; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Optic Nerve Neoplasms; Pituitary Neoplasms; Time Factors
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 226364
Reference URL https://collections.lib.utah.edu/ark:/87278/s6vm7jb7/226364
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