Bilateral Isolated Lateral Geniculate Body Lesions in a Patient with Pancreatitis and Microangiopathy

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Title Journal of Neuro-Ophthalmology, September 2007, Volume 27, Issue 3
Date 2007-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s68087qb
Setname ehsl_novel_jno
ID 225618
Reference URL https://collections.lib.utah.edu/ark:/87278/s68087qb

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Title Bilateral Isolated Lateral Geniculate Body Lesions in a Patient with Pancreatitis and Microangiopathy
Creator Mudumbai, RC; Bhandari, A
Affiliation Department of Ophthalmology, University of Washington, 1959 Pacific Avenue NE, Seattle, WA 98195, USA. raghum@u.washington.edu
Abstract An 18-year-old woman developed pancreatitis and a thrombotic microangiopathy but no electrolyte abnormalities. She required intubation hours after admission and was not able to communicate for 8 days. Upon recovering consciousness, she reported severely impaired vision in both eyes, but ophthalmologic evaluation and neuroimaging were not obtained until several days later. Ophthalmologic examination documented retinal infarcts and profound binocular vision loss with hourglass bilateral homonymous hemianopic visual field loss. MRI showed signal abnormalities restricted to the area of the lateral geniculate bodies (LGBs) with characteristics most suggestive of hemorrhagic infarction. Very few cases of isolated bilateral LBG lesions have been reported. Damage has been attributed to myelinolysis from osmotic demyelination or to infarction from microvascular occlusion. This case conforms more to microvascular infarction. The vulnerability of the LGB to selective microvascular infarction may be based on a combination of its unique architecture and high metabolic demand.
Subject Adolescent; Brain Infarction, etiology; Brain Infarction, pathology; Brain Infarction, physiopathology; Brain Ischemia, etiology; Brain Ischemia, pathology; Brain Ischemia, physiopathology; Disease Progression; Female; Functional Laterality, physiology; Geniculate Bodies, blood supply; Geniculate Bodies, pathology; Geniculate Bodies, physiopathology; Humans; Intracranial Hemorrhages, etiology; Intracranial Hemorrhages, pathology; Intracranial Hemorrhages, physiopathology; Pancreatitis, complications; Peripheral Vascular Diseases, complications; Recovery of Function; Renal Artery Obstruction, complications; Retina, pathology; Retina, physiopathology; Retinal Artery, pathology; Retinal Artery, physiopathology; Retinal Degeneration, etiology; Retinal Degeneration, pathology; Retinal Degeneration, physiopathology; Thalamic Diseases, etiology; Thalamic Diseases, pathology; Thalamic Diseases, physiopathology; Vision, Low, etiology; Vision, Low, pathology; Vision, Low, physiopathology; Visual Fields, physiology
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 225605
Reference URL https://collections.lib.utah.edu/ark:/87278/s68087qb/225605
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